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sounds like a virus, i have seen that on more than one occasion, really wierd cd rom issues. one drive works, another doesn't. i think it's one of the bugbear or sasser varients that does it. check your virus definitions and do a full system scan. you were probably lucky and restored back to a point before the virus infected your system.
and if it's not a virus, it's either really freaky, or some other IDE utility or maybe a via miniport driver (on the off chance you have a via chipset) that messed up your atapi devices on the ide chain.
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