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There are other reasons to do drugs and you can become depressed without the aid of drugs.
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You sure can! But continued use of drugs on an regular and heavy basis or what is usually considered addiction will skew your brain chemistry causing depression and distorted self image in the person that may have not otherwise become depressed.
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Before xtacy was outlawed it was used by clinical phychiatrists to aid patients express thier thoughts, heck even tibeten monks used it because it aided thier medatation.
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Right, show me your documentation.. I doubt Monks were doing Ecstasy.

Since it has only been around for 20 years or so..
It's a garbage drug produced in a lab.
Unlike LSD which is replicated in a lab but derived from a form of mold, in the Ergot class. Which by the way is also garbage.
Drugs suck.
BTW and for the record, I know of what I speak, I'm a recovering addict.