There is a recent TechIMO Team crunching Find-a-Drug, which uses idle CPU cycles very nicely. It runs research for the same university project that UD (mentioned by Wizzard above

). The TechIMO FaD thread is
here
This is the most well-run and most worthwhile DC currently available, IMO.
Good luck in whatever you decide to crunch.
Cheers
Mick
BTW, this thread should probably be in the DC forum - any mod wanna move it?