e is a constant in the sense that any number is a constant.
First off, e is a number, just like pi is a number.
e ~= 2.71828
Remembering that e is a number, any function of e^x evaluates as any other constant.
d/dx ( 2^x) = ln(2) * 2 ^ x is how you would do a number to an exponent, but since ln(e) = 1 (they are inverses)
d/dx (e^x) = ln(e) * e^x = e^x
Also,
d/dx (2^2x) = 2 * ln(2) * 2^2x
so in turn, d/dx (e^2x) = 2 * ln(e) * e^2x
e evaluates exactly the same as anything else, its just that ln(e) = 1 allowing for simplification.
The same applies for integrals if you would like to step backwards
Jkrohn