I agree with Atomic Rooster on Comfortably Numb. I saw Pink Floyd perform The Wall in 1980 in Los Angeles. When David Gilmour played that solo, he was standing on top of the wall. It made my spine shiver! Awesome!
Oh, yeah -- Layla and Samba Pa Ti, absolutely! Also from Carlos, Europa - Earth's Cry, Heaven's Smile. Oh, and then there's Mediterranean Sundance by Al DiMeola and Paco DeLucia. (Guess that's more than one, though.)